Computer aided FCD lesion detection based on T1 MRI data

Focal cortical dysplasia (FCD) is a frequent cause of epilepsy and can be detected using brain magnetic resonance imaging (MRI). The FCD lesions in MRI images are characterized by blurring of the gray matter/white matter (GM/WM) junction, cortical thickening and hyper-intensity signal within lesional region compared with other cortical regions. However, detecting FCD lesions by means of visual inspection can be a very difficult task for radiologists because the lesions are very subtle. To assist physicians in detecting the FCD lesions more efficiently and reduce the false positive regions resulted from the existing methods, we propose an algorithm for automated FCD detection based on T1 MRI data

Multiple classifier fusion and optimization for automatic focal cortical dysplasia detection on magnetic resonance images

In magnetic resonance (MR) images, detection of focal cortical dysplasia (FCD) lesion as a main pathological cue of epilepsy is challenging because of the variability in the presentation of FCD lesions. Existing algorithms appear to have sufficient sensitivity in detecting lesions but also generate large numbers of false-positive (FP) results. In this paper, we propose a multiple classifier fusion and optimization schemes to automatically detect FCD lesions in MR images with reduced FPs through constructing an objective function based on the F-score. Thus, the proposed scheme obtains an improved tradeoff between minimizing FPs and maximizing true positives. The optimization is achieved by incorporating the genetic algorithm into the work scheme. Hence, the contribution of weighting coefficients to different classifications can be effectively determined. The resultant optimized weightings are applied to fuse the classification results. A set of six typical FCD features and six corresponding Z-score maps are evaluated through the mean F-score from multiple classifiers for each feature. From the experimental results, the proposed scheme can automatically detect FCD lesions in 9 out of 10 patients while correctly classifying 31 healthy controls. The proposed scheme acquires a lower FP rate and a higher F-score in comparison with two state-of-the-art methods

A Building Segmentation Network Based on Improved Spatial Pyramid in Remote Sensing Images

Building segmentation is widely used in urban planning, disaster prevention, human flow monitoring and environmental monitoring. However, due to the complex landscapes and highdensity settlements, automatically characterizing building in the urban village or cities using remote sensing images is very challenging. Inspired by the rencent deep learning methods, this paper proposed a novel end-to-end building segmentation network for segmenting buildings from remote sensing images. The network includes two branches: one branch uses Widely Adaptive Spatial Pyramid (WASP) structure to extract multi-scale features, and the other branch uses a deep residual network combined with a sub-pixel up-sampling structure to enhance the detail of building boundaries. We compared our proposed method with three state-of-the-art networks: DeepLabv3+, ENet, ESPNet. Experiments were performed using the publicly available Inria Aerial Image Labelling dataset (Inria aerial dataset) and the Satellite dataset II(East Asia). The results showed that our method outperformed the other networks in the experiments, with Pixel Accuracy reaching 0.8421 and 0.8738, respectively and with mIoU reaching 0.9034 and 0.8936 respectively. Compared with the basic network, it has increased by about 25% or more. It can not only extract building footprints, but also especially small building objects

Experimental Study of Multispectral Characteristics of an Unmanned Aerial Vehicle at Different Observation Angles

This study investigates multispectral characteristics of an unmanned aerial vehicle (UAV) at different observation angles by experiment. The UAV and its engine are tested on the ground in the cruise state. Spectral radiation intensities at different observation angles are obtained in the infrared band of 0.9–15 μm by a spectral radiometer. Meanwhile, infrared images are captured separately by long-wavelength infrared (LWIR), mid-wavelength infrared (MWIR), and short-wavelength infrared (SWIR) cameras. Additionally, orientation maps of the radiation area and radiance are obtained. The results suggest that the spectral radiation intensity of the UAV is determined by its exhaust plume and that the main infrared emission bands occur at 2.7 μm and 4.3 μm. At observation angles in the range of 0°–90°, the radiation area of the UAV in MWIR band is greatest; however, at angles greater than 90°, the radiation area in the SWIR band is greatest. In addition, the radiance of the UAV at an angle of 0° is strongest. These conclusions can guide IR stealth technique development for UAVs

Automatic brain atlas in magnetic resonance image for focal cortical dysplasia patients

Brain tissues including cerebellum, thalamus, brain stem, striatum have increased Gray Matter thickness, an important feature of Focal Cortical Dysplasia (FCD) lesions in Magnetic Resonance Images. However, these tissues are not related to FCD lesions. To reduce the False Positive regions in FCD detection, we propose to automatically generate a brain atlas for every FCD patient. As a result, the brain tissues are successfully located without overlaping the FCD regions.Brain tissues including cerebellum, thalamus, brain stem, striatum have increased Gray Matter thickness, an important feature of Focal Cortical Dysplasia (FCD) lesions in Magnetic Resonance Images. However, these tissues are not related to FCD lesions. To reduce the False Positive regions in FCD detection, we propose to automatically generate a brain atlas for every FCD patient. As a result, the brain tissues are successfully located without overlaping the FCD regions

Estimating blur at the brain gray-white matter boundary for FCD detection in MRI

Focal cortical dysplasia (FCD) is a frequent cause of epilepsy and can be detected using brain magnetic resonance imaging (MRI). One important MRI feature of FCD lesions is the blurring of the gray-white matter boundary (GWB), previously modelled by the gradient strength. However, in the absence of additional FCD descriptors, current gradient-based methods may yield false positives. Moreover, they do not explicitly quantify the level of blur which prevents from using them directly in the process of automated FCD detection. To improve the detection of FCD lesions displaying blur, we develop a novel algorithm called iterating local searches on neighborhood (ILSN). The novelty is that it measures the width of the blurry region rather than the gradient strength. The performance of our method is compared with the gradient magnitude method using precision and recall measures. The experimental results, tested on MRI data of 8 real FCD patients, indicate that our method has higher ability to correctly identify the FCD blurring than the gradient method

Local Directional Probability Optimization for Quantification of Blurred Gray/White Matter Junction in Magnetic Resonance Image

The blurred gray/white matter junction is an important feature of focal cortical dysplasia (FCD) lesions. FCD is the main cause of epilepsy and can be detected through magnetic resonance (MR) imaging. Several earlier studies have focused on computing the gradient magnitude of the MR image and used the resulting map to model the blurred gray/white matter junction. However, gradient magnitude cannot quantify the blurred gray/white matter junction. Therefore, we proposed a novel algorithm called local directional probability optimization (LDPO) for detecting and quantifying the width of the gray/white matter boundary (GWB) within the lesional areas. The proposed LDPO method mainly consists of the following three stages: (1) introduction of a hidden Markov random field-expectation-maximization algorithm to compute the probability images of brain tissues in order to obtain the GWB region; (2) generation of local directions from gray matter (GM) to white matter (WM) passing through the GWB, considering the GWB to be an electric potential field; (3) determination of the optimal local directions for any given voxel of GWB, based on iterative searching of the neighborhood. This was then used to measure the width of the GWB. The proposed LDPO method was tested on real MR images of patients with FCD lesions. The results indicated that the LDPO method could quantify the GWB width. On the GWB width map, the width of the blurred GWB in the lesional region was observed to be greater than that in the non-lesional regions. The proposed GWB width map produced higher F-scores in terms of detecting the blurred GWB within the FCD lesional region as compared to that of FCD feature maps, indicating better trade-off between precision and recall